Description

Methyl 3-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-value, multifunctional boronic ester derivative that serves as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex biaryl and heterobiaryl structures in modern organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biphenyl or phenolic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic frameworks.
• Material Science: Serves as a monomer or precursor for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research: An indispensable reagent in academic and industrial R&D labs for exploring new catalytic processes and constructing complex molecular architectures.
• Ligand and Catalyst Development: Utilized to synthesize novel bidentate or polydentate ligands for metal catalysis and sensing applications.
• Suzuki-Miyaura Cross-Coupling: The primary application, enabling the formation of carbon-carbon bonds between its boronate group and various organic halides under palladium catalysis.

Basic Information

Product Name	Methyl 3-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1004294-79-4
Molecular Formula	C14H19BO5
Molecular Weight	278.11 g/mol
Synonyms	3-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-hydroxybenzoic acid methyl ester; 3-Hydroxy-5-(pinacolatoboryl)benzoic acid methyl ester; Methyl 3-hydroxy-5-(pinacolatoboryl)benzoate; Methyl 5-(pinacolboronato)-3-hydroxybenzoate; Benzoic acid, 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.