Description

2-Bromo-1-(4-Bromo-3-Fluorophenyl)Ethanone is a high-purity, multi-functional halogenated aromatic ketone building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, due to its reactive bromine and fluorine substituents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and anti-cancer drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Functional Group Transformation: The reactive α-bromo ketone moiety allows for further derivatization to alcohols, amines, and heterocycles.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Bromo-1-(4-Bromo-3-Fluorophenyl)Ethanone
CAS No.	1003879-02-4
Molecular Formula	C8H5Br2FO
Molecular Weight	295.93 g/mol
Synonyms	2-Bromo-1-(4-bromo-3-fluorophenyl)ethan-1-one; 1-(4-Bromo-3-fluorophenyl)-2-bromoethanone; 4'-Bromo-3'-fluoro-2-bromoacetophenone; α,4-Dibromo-3-fluoroacetophenone; 2-Bromo-4'-bromo-3'-fluoroacetophenone; 2,4-Dibromo-3-fluoroacetophenone; (4-Bromo-3-fluorophenyl)-2-bromoethanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Bromo-3-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.