Description

3,5-Dichloro-4-Hydroxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides requiring specific chlorinated phenolic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and ligands for studying biological pathways and protein interactions.
• Fine Chemical Production: Acts as a versatile synthon for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3,5-Dichloro-4-Hydroxyphenylboronic Acid Pinacol Ester
CAS No.	1003298-87-0
Molecular Formula	C₁₂H₁₅BCl₂O₃
Molecular Weight	289.96 g/mol
Synonyms	2-(3,5-Dichloro-4-hydroxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Hydroxy-3,5-dichlorobenzeneboronic Acid Pinacol Ester; (3,5-Dichloro-4-hydroxyphenyl)boronic Acid Pinacol Ester; 3,5-Dichloro-4-hydroxybenzeneboronic Acid Pinacol Ester; B-(3,5-Dichloro-4-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3,5-Dichloro-4-hydroxyphenyl)boronate
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-Hydroxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.