Description

6-Chloro-5-Methylpyridine-3-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic components.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in constructing pyridine-based herbicides, fungicides, and insecticides, contributing to the development of next-generation crop protection agents.
• Material Science Precursor: Serves as a building block for creating functionalized polymers, ligands for catalysts, and organic semiconductors for electronic devices.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Used to prepare sophisticated bidentate or tridentate ligands for transition metal catalysis.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic acid coupling partner with aryl/heteroaryl halides to form biaryl and heterobiaryl structures.

Basic Information

Product Name	6-Chloro-5-Methylpyridine-3-Boronic Acid
CAS No.	1003043-40-0
Molecular Formula	C6H7BClNO2
Molecular Weight	171.39 g/mol
Synonyms	(6-Chloro-5-methylpyridin-3-yl)boronic acid; 5-Methyl-6-chloropyridine-3-boronic acid; 3-Borono-6-chloro-5-methylpyridine; 6-Chloro-5-methyl-3-pyridineboronic acid; Boronic acid, B-(6-chloro-5-methyl-3-pyridinyl)-; 1003043-40-0; 6-Chloro-5-methylpyridin-3-ylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-5-Methylpyridine-3-Boronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation (by 1H NMR and IR), and impurity profile is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.