Description

2-Bromo-3-Chloropyridine-4-Boronic Acid is a high-value, multi-functional heterocyclic boronic acid building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and diagnostic agents for biological target identification.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to introduce the pyridine core into more complex structures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	2-Bromo-3-Chloropyridine-4-Boronic Acid
CAS No.	1003043-31-9
Molecular Formula	C5H4BBrClNO2
Molecular Weight	236.26 g/mol
Synonyms	(2-Bromo-3-chloropyridin-4-yl)boronic acid; 2-Bromo-3-chloro-4-pyridineboronic acid; 4-Borono-2-bromo-3-chloropyridine; 3-Chloro-2-bromopyridine-4-boronic acid; 1003043-31-9; 2-Bromo-3-chloro-4-pyridylboronic acid; 2-Br-3-Cl-4-PyB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloropyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.