Description

2-Chloro-5-Hydroxymethylphenylboronic Acid is a versatile and synthetically valuable boronic acid derivative. This compound serves as a crucial building block in modern organic synthesis, particularly in cross-coupling reactions to form new carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides by constructing complex biaryl structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and organometallic chemistry research.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-5-Hydroxymethylphenylboronic Acid
CAS No.	1003042-59-8
Molecular Formula	C7H8BClO3
Molecular Weight	186.40 g/mol
Synonyms	(2-Chloro-5-(hydroxymethyl)phenyl)boronic acid; 2-Chloro-5-(hydroxymethyl)benzeneboronic acid; 5-(Hydroxymethyl)-2-chlorophenylboronic acid; B-(2-Chloro-5-(hydroxymethyl)phenyl)boronic acid; 2-Chloro-5-hydroxymethylbenzeneboronic acid; 1003042-59-8; Boronic acid, B-[2-chloro-5-(hydroxymethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Hydroxymethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical synthesis applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.