Description

20-Deoxo-20-(1-Piperidinyl)Tylosin is a semi-synthetic derivative of the macrolide antibiotic tylosin, specifically modified at the 20-position. This chemical modification is significant for enhancing stability and potentially altering the biological activity profile of the parent compound. It serves as a crucial pharmaceutical intermediate and research chemical for the development of novel veterinary and human therapeutics targeting bacterial infections.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced macrolide antibiotics for veterinary and potential human use.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate structure-activity relationships (SAR) against Gram-positive bacteria.
• Veterinary Medicine Development: A precursor in creating formulations for treating respiratory and enteric infections in livestock, such as swine and poultry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in antibiotic manufacturing.
• Chemical Synthesis: Utilized in organic chemistry research for further derivatization to explore new bioactive compounds.

Basic Information

Product Name	20-Deoxo-20-(1-Piperidinyl)Tylosin
CAS No.	1003024-00-7
Molecular Formula	C48H85N3O16
Molecular Weight	960.21 g/mol
Synonyms	20-Deoxo-20-(1-piperidyl)tylosin; 20-Deoxo-20-piperidin-1-yltylosin; Tylosin 20-piperidinyl derivative; 20-Piperidinyltylosin; Antibiotic Tylosin Derivative; (1R,2R,3S,4R,5R,8R,9S,10S,11R,12S,13S,14R)-13-{[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]methyl}-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-9-{[(4R,5S,6S,7R,9R)-5-(dimethylamino)-6-{[(2R,3R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-2-tetrahydropyranyl]oxy}-9-hydroxy-2,4a,7,9-tetramethyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrobenzo[a]azulen-7-yl]oxy}-11-[(1-piperidinyl)methyl]-1,4a,5,6,7,8,9,10,10a,11-decahydro-1H-2-benzoxacyclotetradecin-6-one
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Quality Control

Our 20-Deoxo-20-(1-Piperidinyl)Tylosin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.