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6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Chroman, 97% CAS NO 1002727-88-9


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CAS No.:1002727-88-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Chroman, 97% is a high-purity boronic ester derivative of chroman, serving as a versatile and critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in constructing chroman-based scaffolds prevalent in therapeutic agents.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the chroman structural motif.
  • Material Science & Organic Electronics: Serves as a precursor for creating organic semiconductors, light-emitting materials, and advanced polymers with specific electronic properties.
  • Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for methodology development and exploring new synthetic routes via palladium-catalyzed cross-coupling.
  • Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance, flavor, and dye molecules.

Basic Information

Item Detail
Product Name 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Chroman, 97%
CAS No. 1002727-88-9
Molecular Formula C15H21BO3
Molecular Weight 260.14 g/mol
Synonyms 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1-benzopyran; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman; Chroman-6-boronic acid pinacol ester; 6-Chromanboronic acid pinacol ester; 2-(3,4-Dihydro-2H-1-benzopyran-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-(Pinacolatoboryl)chroman
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Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Chroman, 97% is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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