Description

3-(Methoxymethyl)-5-Methylisoxazol-4-Ylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel drug candidates and advanced agrochemical intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the isoxazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Serves as a precursor for creating advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for forming carbon-carbon bonds between the isoxazole ring and various aryl or vinyl halides, enabling rapid molecular diversification.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of chemical probes and tool compounds for target validation and biological pathway studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	3-(Methoxymethyl)-5-Methylisoxazol-4-Ylboronic Acid
CAS No.	1000894-08-5
Molecular Formula	C7H12BNO4
Molecular Weight	185.00 g/mol
Synonyms	3-(Methoxymethyl)-5-methyl-4-isoxazoleboronic acid; 5-Methyl-3-(methoxymethyl)isoxazole-4-boronic acid; 4-Borono-3-(methoxymethyl)-5-methylisoxazole; (3-(Methoxymethyl)-5-methylisoxazol-4-yl)boronic acid; B-[3-(Methoxymethyl)-5-methyl-4-isoxazolyl]boronic acid
EINECS	Contact for details

Quality Control

Our 3-(Methoxymethyl)-5-Methylisoxazol-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.