Description

1-[2-(1-Piperidyl)Ethyl]-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its role in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used in palladium-catalyzed reactions to form carbon-carbon bonds, essential for constructing complex heterocyclic scaffolds.
• Agrochemical Research: Employed in the development of new pesticides and herbicides with specific biological activity.
• Material Science: Serves as a precursor for functional organic materials and ligands for catalysis.
• Chemical Biology Probes: Used in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis.

Basic Information

Product Name	1-[2-(1-Piperidyl)Ethyl]-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	1000802-51-6
Molecular Formula	C16H28BN3O2
Molecular Weight	305.22 g/mol
Synonyms	1-[2-(1-Piperidyl)ethyl]-1H-pyrazole-4-boronic acid pinacol ester; 1-(2-Piperidin-1-ylethyl)-1H-pyrazole-4-boronic acid pinacol ester; 1H-Pyrazole-4-boronic acid, 1-[2-(1-piperidinyl)ethyl]-, 1,1,1,1-tetramethyl-2-propanyl ester; 1-(2-(Piperidin-1-yl)ethyl)-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-[2-(piperidin-1-yl)ethyl]-1H-pyrazole; B-1H-Pyrazol-4-ylboronic acid pinacol ester derivative.
EINECS	Contact for details

Quality Control

Our 1-[2-(1-Piperidyl)Ethyl]-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon in a desiccator.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.