Description

2,4-Dibromo-5-Fluoroiodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique combination of bromine, fluorine, and iodine substituents allows for selective, sequential cross-coupling reactions, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring selective halogenation patterns for bioactivity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where specific halogen atoms are crucial for efficacy.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings, where the different halogens allow for sequential, site-specific functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,4-Dibromo-5-Fluoroiodobenzene
CAS No.	1000578-13-1
Molecular Formula	C6H2Br2FI
Molecular Weight	403.79 g/mol
Synonyms	1,3-Dibromo-4-fluoro-2-iodobenzene; 5-Fluoro-2,4-dibromo-1-iodobenzene; Benzene, 1,3-dibromo-4-fluoro-2-iodo-; 2-Iodo-1,3-dibromo-4-fluorobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-5-Fluoroiodobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.