Description

2-Amino-5-Bromo-3-Iodobenzonitrile is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates three distinct halogen atoms (bromine, iodine) and a nitrile group, enabling precise and diverse functionalization for creating complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and halogen substituents.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination, where the bromine and iodine atoms offer orthogonal reactivity.
• Chemical Biology: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized dyes and functional pigments.

Basic Information

Product Name	2-Amino-5-Bromo-3-Iodobenzonitrile
CAS No.	1000577-44-5
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	5-Bromo-3-iodo-2-aminobenzonitrile; 2-Amino-5-bromo-3-iodobenzonitrile; Benzonitrile, 2-amino-5-bromo-3-iodo-; 5-Bromo-3-iodoanthranilonitrile; 2-Cyano-4-bromo-6-iodoaniline
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.