Description

4-Bromo-3,5-Dichloroiodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of bromo, chloro, and iodo substituents on a single aromatic ring makes it exceptionally valuable for constructing complex molecular architectures through selective cross-coupling and substitution reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring halogen-rich aromatic cores for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the halogen pattern is crucial for biological activity.
• Material Science Building Block: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its ability to undergo various metal-catalyzed coupling reactions.
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and Sonogashira couplings, where the different halogens offer orthogonal reactivity for sequential functionalization.
• Ligand and Catalyst Development: Utilized in the synthesis of sophisticated polydentate ligands and organocatalysts for asymmetric synthesis.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Item	Detail
Product Name	4-Bromo-3,5-Dichloroiodobenzene
CAS No.	1000574-29-7
Molecular Formula	C6H2BrCl2I
Molecular Weight	366.25 g/mol
Synonyms	1-Bromo-2,4-dichloro-5-iodobenzene; 2,4-Dichloro-1-bromo-5-iodobenzene; 4-Bromo-3,5-dichloro-1-iodobenzene; Benzene, 1-bromo-2,4-dichloro-5-iodo-; 5-Iodo-4-bromo-1,3-dichlorobenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3,5-Dichloroiodobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.