Description

1-Bromo-2,3-Dichloro-4-Iodo-Benzene is a highly functionalized halogenated benzene derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its precise substitution pattern makes it a critical intermediate for constructing complex molecules where specific halogen atoms are required for subsequent cross-coupling or substitution reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the halogen atoms enable further functionalization.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi coupling reactions due to the presence of bromo and iodo substituents, which have distinct reactivity profiles.
• Chemical Synthesis Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Bromo-2,3-Dichloro-4-Iodo-Benzene
CAS No.	1000574-05-9
Molecular Formula	C6H2BrCl2I
Molecular Weight	366.25 g/mol
Synonyms	2,3-Dichloro-4-iodo-1-bromobenzene; 1-Bromo-2,3-dichloro-4-iodobenzene; Benzene, 1-bromo-2,3-dichloro-4-iodo-; 4-Iodo-2,3-dichlorobromobenzene; 2,3-Dichloro-1-bromo-4-iodobenzene; Bromo-dichloro-iodobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2,3-Dichloro-4-Iodo-Benzene is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.