Description

1,3-Dibromo-2,4-dichloro-5-fluorobenzene is a highly functionalized, multi-halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules where specific regiochemistry is paramount. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring specific halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides where the fluorine and chlorine/bromine atoms contribute to efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Library Development: Employed in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Cross-Coupling Reactions: An excellent substrate for selective metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the differential reactivity of its bromine and chlorine atoms.
• Fluorine Chemistry Studies: A valuable reagent for investigating the influence of fluorine atoms on aromatic systems in relation to neighboring halogen substituents.

Basic Information

Item	Detail
Product Name	1,3-Dibromo-2,4-dichloro-5-fluorobenzene
CAS No.	1000573-45-4
Molecular Formula	C6HBr2Cl2F
Molecular Weight	322.78 g/mol
Synonyms	2,4-Dichloro-1,3-dibromo-5-fluorobenzene; 5-Fluoro-1,3-dibromo-2,4-dichlorobenzene; 1,3-Dibromo-2,4-dichloro-5-fluorobenzene; Benzene, 1,3-dibromo-2,4-dichloro-5-fluoro-; 2,4-Dichloro-5-fluoro-1,3-dibromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dibromo-2,4-dichloro-5-fluorobenzene is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.