Description

4-Bromo-3-Chloro-2-Fluoroiodobenzene is a highly functionalized, multi-halogenated benzene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting complex biological pathways.
• Agrochemical Research: Used to construct novel herbicides, fungicides, and insecticides by introducing specific halogen patterns that influence bioactivity and environmental fate.
• Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of multiple, differentially reactive halogen atoms.
• Ligand Synthesis: Employed in the preparation of complex, polydentate ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and diagnostic applications.

Basic Information

Item	Details
Product Name	4-Bromo-3-Chloro-2-Fluoroiodobenzene
CAS No.	1000573-03-4
Molecular Formula	C6H2BrClFI
Molecular Weight	335.34 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-4-iodobenzene; 2-Fluoro-3-chloro-4-bromoiodobenzene; Benzene, 1-bromo-2-chloro-3-fluoro-4-iodo-; 4-Bromo-3-chloro-2-fluoro-1-iodobenzene; 3-Chloro-4-bromo-2-fluoroiodobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-2-Fluoroiodobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.