Description

Cyclopropanepropanoic Acid, B-Oxo-1-(Trifluoromethyl)- is a high-value, fluorinated organic building block characterized by its cyclopropane and β-keto acid functionalities. This compound matters as a versatile synthon for introducing the trifluoromethyl group and strained ring systems into complex molecules, which is critical for modulating the physicochemical properties of target compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal and chemical resistance properties.
• Fluorine Chemistry: An essential reagent for studying structure-activity relationships (SAR) and for the late-stage functionalization of complex molecules with fluorine-containing motifs.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development in organic synthesis and catalysis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	Cyclopropanepropanoic Acid, B-Oxo-1-(Trifluoromethyl)-
CAS No.	1000525-62-1
Molecular Formula	C7H7F3O3
Molecular Weight	196.13 g/mol
Synonyms	3-Oxo-1-(trifluoromethyl)cyclopropane-1-propanoic Acid; 1-(Trifluoromethyl)-3-oxocyclopropanepropanoic Acid; β-Oxo-1-(trifluoromethyl)cyclopropanepropanoic Acid; 3-Oxo-1-(trifluoromethyl)cyclopropylpropanoic Acid; 1-(Trifluoromethyl)-3-oxocyclopropylpropanoic Acid; (1-(Trifluoromethyl)-3-oxocyclopropyl)propanoic Acid; 3-(1-(Trifluoromethyl)-3-oxocyclopropyl)propanoic Acid
EINECS	Contact for details

Quality Control

Our production of Cyclopropanepropanoic Acid, B-Oxo-1-(Trifluoromethyl)- adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against comprehensive specifications using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.