Description

4-Fluoro-4-Hydroxymethyl-1-Methylpiperidine is a high-value, multi-functional piperidine derivative featuring both fluorinated and hydroxymethyl substituents. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorine atom and modifiable hydroxymethyl group.
• Agrochemical Synthesis: Serves as a precursor for novel fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance biological activity and stability.
• Ligand and Catalyst Development: Utilized in the synthesis of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent or affinity probes to study biological targets and pathways.
• Material Science Research: A potential monomer or modifier for creating specialty polymers with unique surface properties.

Basic Information

Product Name	4-Fluoro-4-Hydroxymethyl-1-Methylpiperidine
CAS No.	1000341-04-7
Molecular Formula	C7H14FNO
Molecular Weight	147.19 g/mol
Synonyms	1-Methyl-4-fluoro-4-(hydroxymethyl)piperidine; 4-Fluoro-1-methyl-4-piperidinemethanol; 4-(Hydroxymethyl)-4-fluoro-1-methylpiperidine; 4-Fluoro-4-(hydroxymethyl)-1-methylpiperidine; 1-Methyl-4-fluoro-4-piperidinemethanol; 4-Fluoro-1-methylpiperidine-4-methanol; 4-Fluoro-4-(hydroxymethyl)-N-methylpiperidine
EINECS	Contact for details

Quality Control

Our 4-Fluoro-4-Hydroxymethyl-1-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.