Description

3-{2-[4-(Trifluoromethyl)Piperidino]Ethyl}Benzenecarbaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted piperidine moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system and other therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of the trifluoromethyl-piperidine group on potency and selectivity.
• Agrochemical Development: Serves as a precursor in the research of novel pesticides and herbicides, leveraging the stability imparted by the fluorine atoms.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis or biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	3-{2-[4-(Trifluoromethyl)Piperidino]Ethyl}Benzenecarbaldehyde
CAS No.	1000339-89-8
Molecular Formula	C15H18F3NO
Molecular Weight	285.31 g/mol
Synonyms	3-[2-[4-(Trifluoromethyl)piperidin-1-yl]ethyl]benzaldehyde; 1-[2-(3-Formylphenyl)ethyl]-4-(trifluoromethyl)piperidine; 3-(2-(4-(Trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde; m-[2-[4-(Trifluoromethyl)-1-piperidinyl]ethyl]benzaldehyde; Benzaldehyde, 3-[2-[4-(trifluoromethyl)-1-piperidinyl]ethyl]-; CAS 1000339-89-8
EINECS	Contact for details

Quality Control

Every batch of 3-{2-[4-(Trifluoromethyl)Piperidino]Ethyl}Benzenecarbaldehyde is manufactured under a strict quality management system. Our products undergo rigorous analytical testing to ensure compliance with exacting purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.