Description

Butyl2,2-Difluorobutanoate CAS NO 1000339-45-6 is a specialized fluorinated ester compound, serving as a valuable building block in advanced organic synthesis. Its molecular structure, featuring a difluoromethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modifying their physical, chemical, and biological properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity fluorinated intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of drugs where fluorination enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoro moiety can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric materials.
• Polymer Modification: Employed to create fluorinated monomers or additives that impart unique properties like oil repellency, chemical resistance, or low surface energy to polymers.
• Organic Synthesis Reagent: Acts as a versatile reagent in nucleophilic substitution and condensation reactions to incorporate the 2,2-difluorobutanoate moiety.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research exploring structure-activity relationships (SAR) influenced by fluorine.

Basic Information

Product Name	Butyl2,2-Difluorobutanoate
CAS No.	1000339-45-6
Molecular Formula	C8H14F2O2
Molecular Weight	180.19 g/mol
Synonyms	Butyl 2,2-Difluorobutanoate; 2,2-Difluorobutanoic Acid Butyl Ester; n-Butyl 2,2-Difluorobutanoate; Butyl α,α-Difluorobutanoate; 2,2-Difluorobutanoic Acid n-Butyl Ester; Butyl 2,2-Difluorobutyrate; Difluorobutanoic Acid Butyl Ester
EINECS	Contact for details

Quality Control

Our Butyl2,2-Difluorobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.390 - 1.400 @ 20°C
Density	1.05 - 1.15 g/mL @ 25°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.