Description

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a versatile and high-value boronic ester derivative of an aniline compound, serving as a critical synthetic intermediate. Its primary value lies in enabling efficient cross-coupling reactions, most notably the Suzuki-Miyaura reaction, which is fundamental for constructing complex organic frameworks. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling to introduce functional aromatic groups.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Acts as a monomer or functionalization agent for creating specialty polymers with tailored electronic or mechanical properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in synthetic organic chemistry for constructing complex, biaryl-linked structures.

Basic Information

Item	Detail
Product Name	2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1000339-10-5
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	5-Amino-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; (5-Amino-2-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-5-(pinacolatoboryl)aniline; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxyaniline; 2-Methoxy-5-boronoaniline pinacol ester; AN-012/43429001
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.