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Benzo[B]Thiophen-4-Ylboronic Acid Pinacol Ester CAS NO 1000160-75-7


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CAS No.:1000160-75-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzo[B]Thiophen-4-Ylboronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a boronic ester derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to construct complex heterocyclic scaffolds.

Application

  • Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing benzothiophene or related heterocyclic cores.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the construction of complex molecular architectures.
  • Material Science: Serves as a precursor in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
  • Chemical Synthesis: Enables Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl structures with high efficiency and functional group tolerance.
  • Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
  • Life Sciences & Diagnostics: Acts as a building block for fluorescent probes, biomarkers, and other molecular tools used in biochemical research.

Basic Information

Item Detail
Product Name Benzo[B]Thiophen-4-Ylboronic Acid Pinacol Ester
CAS No. 1000160-75-7
Molecular Formula C14H17BO2S
Molecular Weight 260.16 g/mol
Synonyms 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophene; Benzo[b]thiophen-4-ylboronic acid pinacol ester; 2-(Benzo[b]thiophen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Benzo[b]thienylboronic acid pinacol ester; BT-4-BPin
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Quality Control

Our Benzo[B]Thiophen-4-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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