Description

2-(Benzo[B]Thiophen-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for constructing complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing benzothiophene scaffolds, used in drug discovery and development.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Used in the production of electron-transport materials and emissive layer components for display and lighting technologies.
• Material Science Research: Facilitates the creation of novel organic semiconductors, conductive polymers, and liquid crystals.
• Cross-Coupling Reactions: Serves as a versatile boronic ester partner in Suzuki-Miyaura couplings for constructing biaryl and heterobiaryl systems.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	2-(Benzo[B]Thiophen-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1000160-74-6
Molecular Formula	C16H21BO2S
Molecular Weight	288.21 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophene; Benzo[b]thiophen-7-ylboronic acid pinacol ester; 7-Benzo[b]thienylboronic acid pinacol ester; 2-(Benzo[b]thiophen-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzothiophene; BTTM; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzo[B]Thiophen-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.