Description

1H-Indole-1-Carboxylic Acid, 2-Borono-6-Fluoro-, 1-(1,1-Dimethylethyl) Ester is a high-value, multi-functional boron-containing indole derivative. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures through versatile cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: The boronic ester functionality makes it an essential reagent for forming carbon-carbon bonds in medicinal chemistry and material science.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Serves as a precursor for creating fluorescent or affinity tags to study biological processes.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-6-Fluoro-, 1-(1,1-Dimethylethyl) Ester
CAS No.	1000068-26-7
Molecular Formula	C₁₃H₁₅BFNO₄
Molecular Weight	279.07 g/mol
Synonyms	2-Borono-6-fluoro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 2-borono-6-fluoro-1H-indole-1-carboxylate; 6-Fluoro-1-(tert-butoxycarbonyl)indole-2-boronic acid; 6-Fluoro-1-Boc-indole-2-boronic acid; 6-Fluoro-1-N-Boc-indole-2-boronic acid; 2-Boron-6-fluoro-1H-indole-1-carboxylic acid tert-butyl ester; 6-Fluoro-2-borono-1H-indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2-Borono-6-Fluoro-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.