Description

5-(2-Fluorophenyl)-5-Oxovaleric Acid is a high-purity fluorinated organic building block with the CAS registry number 199664-70-5. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs). Its unique structure offers a versatile handle for further chemical modifications essential in modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel therapeutic agents, especially for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in multi-step synthetic routes for fluorinated drug candidates.
• Biochemical Research: Used in proteomics and medicinal chemistry research to study enzyme interactions and structure-activity relationships (SAR).
• Organic Synthesis Building Block: Employed in constructing complex organic molecules for material science and agrochemical research due to its reactive ketone and carboxylic acid functionalities.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-(2-Fluorophenyl)-5-Oxovaleric Acid
CAS No.	199664-70-5
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	5-Oxo-5-(2-fluorophenyl)pentanoic acid; 2-Fluoro-γ-oxobenzenepentanoic acid; 5-(2-Fluorobenzoyl)valeric acid; δ-Oxo-δ-(2-fluorophenyl)valeric acid; 4-Carboxybutyl 2-fluorophenyl ketone; 199664-70-5; 5-(2-Fluorophenyl)-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Fluorophenyl)-5-Oxovaleric Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.