Description

5-(3-Nitrophenyl)-3-Isoxazolecarboxylic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific enzymatic pathways. It is needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the isoxazole and nitrophenyl motifs.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in combinatorial chemistry and for studying structure-activity relationships (SAR).
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers with specific electronic or photophysical properties.
• Academic Research: Employed in university and institutional labs for methodological studies in organic synthesis, such as cycloaddition reactions and functional group transformations.

Basic Information

Product Name	5-(3-Nitrophenyl)-3-Isoxazolecarboxylic Acid
CAS No.	199601-80-4
Molecular Formula	C10H6N2O5
Molecular Weight	234.17 g/mol
Synonyms	3-Isoxazolecarboxylic acid, 5-(3-nitrophenyl)-; 5-(3-Nitrophenyl)isoxazole-3-carboxylic acid; 5-(m-Nitrophenyl)-3-isoxazolecarboxylic acid; 3-Carboxy-5-(3-nitrophenyl)isoxazole; 5-(3-Nitro-phenyl)-isoxazole-3-carboxylic acid; 199601-80-4; AI3-52410
EINECS	Contact for details

Quality Control

Our 5-(3-Nitrophenyl)-3-Isoxazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.