Description

4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is a high-purity, multi-functional aromatic carboxylic acid building block. This compound is valued for its unique trifluoromethyl-substituted biphenyl core, which imparts desirable physicochemical properties for advanced synthesis. It is primarily utilized by R&D and production chemists in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. Its structural features make it a critical intermediate for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorine-containing liquid crystals for high-performance displays (LCDs).
• Organic Electronic Materials: Employed in the development of organic semiconductors, electron-transport materials, and components for OLED devices.
• Advanced Material Science: Acts as a monomer or cross-linking agent for creating specialized polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid
CAS No.	199528-28-4
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	[3'-(Trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid]; 3'-Trifluoromethylbiphenyl-3-carboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic Acid; Biphenyl-3-carboxylic acid, 3'-trifluoromethyl-; 3-Carboxy-3'-trifluoromethylbiphenyl
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.