Description

2-Fluoro-5-(Trifluoromethyl)Benzophenone is a high-value fluorinated aromatic ketone building block, distinguished by its unique trifluoromethyl and fluorine substituents. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of materials with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, to construct complex, fluorinated aromatic systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring structure-activity relationships (SAR) and scalable synthetic routes.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Benzophenone
CAS No.	199292-40-5
Molecular Formula	C14H8F4O
Molecular Weight	268.21 g/mol
Synonyms	2-Fluoro-5-(trifluoromethyl)benzophenone; [2-Fluoro-5-(trifluoromethyl)phenyl](phenyl)methanone; 2-Fluoro-α-phenyl-5-(trifluoromethyl)benzenemethanol; Benzophenone, 2-fluoro-5-(trifluoromethyl)-; (2-Fluoro-5-trifluoromethylphenyl)(phenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Benzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.