Description

2,3-Dihydro-2,2-Dimethyl-6-Fluoro-1H-Inden-1-One is a high-value fluorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. Its unique structure, featuring a fluorine atom at the 6-position, is essential for modulating the biological activity, metabolic stability, and lipophilicity of target drug molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring precise molecular tuning.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Precursor: Serves as a starting material for synthesizing specialized fluorinated organic compounds used in advanced materials.
• Chemical Synthesis: Acts as a versatile synthon for introducing the fluorinated indanone moiety into more complex molecular architectures in medicinal chemistry.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	2,3-Dihydro-2,2-Dimethyl-6-Fluoro-1H-Inden-1-One
CAS No.	198341-10-5
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	6-Fluoro-2,2-dimethylindan-1-one; 2,2-Dimethyl-6-fluoroindan-1-one; 6-Fluoro-2,2-dimethyl-2,3-dihydro-1H-inden-1-one; 1H-Inden-1-one, 2,3-dihydro-2,2-dimethyl-6-fluoro-; 2,2-Dimethyl-6-fluoro-2,3-dihydro-1H-inden-1-one; 198341-10-5; Fluorinated Dimethylindanone
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-2,2-Dimethyl-6-Fluoro-1H-Inden-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider using an inert gas blanket (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.