Description

16α-Hydroxy-19,20-Epoxy-20β-Methoxy-Ent-Kaurane is a highly functionalized ent-kaurane diterpenoid derivative, a compound class of significant interest in advanced organic synthesis and pharmaceutical research. Its complex, multi-functional structure makes it a valuable advanced synthetic intermediate and a scaffold for developing novel bioactive molecules. This compound is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new chemical entities and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new biological activities.
• Natural Product Synthesis: An important intermediate in the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and target identification.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value fine chemicals.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in related compound analysis.

Basic Information

Product Name	16α-Hydroxy-19,20-Epoxy-20β-Methoxy-Ent-Kaurane
CAS No.	197369-57-6
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	16α-Hydroxy-19,20-epoxy-20β-methoxy-ent-kaurane; ent-16α-Hydroxy-19,20-epoxy-20β-methoxykaurane; 19,20-Epoxy-16α-hydroxy-20β-methoxy-ent-kaurane; (4aR,5S,6S,8aR,9R,12aR)-6-Hydroxy-5,8a-dimethyl-3-methylene-2,4a,5,6,7,8,8a,9,12,12a-decahydro-1H-11-oxa-cyclobuta[a]phenanthren-9-yl methanol; Kaurane diterpenoid derivative.
EINECS	Contact for details

Quality Control

Our 16α-Hydroxy-19,20-Epoxy-20β-Methoxy-Ent-Kaurane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected by research and development organizations for high-value synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.