Description

2-Butenamide,2-Fluoro-4-Hydroxy-N,n-Dimethyl-,(E)-(9Ci) is a specialized fluorinated amide derivative with a defined (E)-stereochemistry. This compound is a high-value synthetic intermediate prized for its unique molecular scaffold, which combines a reactive α,β-unsaturated amide moiety with fluorine and hydroxyl substituents. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Organic Synthesis Reagent: Acts as a versatile Michael acceptor or electrophile in complex organic transformations and medicinal chemistry campaigns.
• Chemical Research: Employed in academic and industrial R&D settings for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science Precursor: Investigated for the synthesis of specialized polymers or functional materials with tailored properties.

Basic Information

Product Name	2-Butenamide,2-Fluoro-4-Hydroxy-N,n-Dimethyl-,(E)-(9Ci)
CAS No.	197096-97-2
Molecular Formula	C6H10FNO2
Molecular Weight	147.15 g/mol
Synonyms	(E)-2-Fluoro-4-hydroxy-N,N-dimethylbut-2-enamide; 2-Butenamide, 2-fluoro-4-hydroxy-N,N-dimethyl-, (E)-; N,N-Dimethyl-2-fluoro-4-hydroxy-(E)-2-butenamide; 2-Fluoro-4-hydroxy-N,N-dimethylcrotonamide; (E)-2-Fluoro-4-hydroxy-N,N-dimethylcrotonamide; Fluorohydroxydimethylbutenamide
EINECS	Contact for details

Quality Control

Our production of 2-Butenamide,2-Fluoro-4-Hydroxy-N,n-Dimethyl-,(E)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.