Description

Thiophene-2-Boronic Acid, Propanediol Cyclic Ester is a high-purity, protected boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in cross-coupling reactions, offering enhanced stability and reactivity for the precise construction of complex molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific thiophene-based architectures.
• Organic Electronic Materials: Serves as a precursor in the synthesis of conjugated polymers and small molecules for OLEDs, organic photovoltaics, and semiconductors.
• Chemical Research & Development: A versatile building block for creating complex organic molecules in academic and industrial R&D settings.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity boronic ester coupling partners.

Basic Information

Product Name	Thiophene-2-Boronic Acid, Propanediol Cyclic Ester
CAS No.	197024-83-2
Molecular Formula	C9H11BO3S
Molecular Weight	210.06 g/mol
Synonyms	2-Thiopheneboronic Acid 1,3-Propanediol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene (Note: This is a common analog; the propanediol ester is less common); Thiophen-2-ylboronic Acid Cyclic Propylene Ester; 5,5-Dimethyl-2-(thiophen-2-yl)-1,3,2-dioxaborinane; 2-Thienylboronic Acid Propanediol Ester; B-(2-Thienyl)-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our Thiophene-2-Boronic Acid, Propanediol Cyclic Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided to guarantee the material meets your specific research or production-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.