Description

(-)-Diisopropyl O,O'-Bis(Trimethylsilyl) -D-Tartrate is a high-purity, chiral silyl-protected tartrate derivative, a key building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and ligand precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral intermediates for complex synthetic routes. The product is identified by CAS No. 197013-45-9.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions, including aldol, Diels-Alder, and hydrogenation reactions.
• Pharmaceutical Intermediates: A critical building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Catalyst Development: Serves as a precursor for novel chiral catalysts and organocatalysts used in academic and industrial research.
• Fine Chemical Production: Integral to the manufacture of specialty flavors, fragrances, and other high-value chiral compounds.
• Material Science: Potential use in the development of chiral polymers and liquid crystals for advanced optical applications.

Basic Information

Product Name	(-)-Diisopropyl O,O'-Bis(Trimethylsilyl) -D-Tartrate
CAS No.	197013-45-9
Molecular Formula	C16H36O6Si2
Molecular Weight	380.63 g/mol
Synonyms	(-)-Diisopropyl O,O'-Bis(trimethylsilyl)-D-tartrate; D-(-)-Diisopropyl O,O'-Bis(trimethylsilyl)tartrate; (2R,3R)-Diisopropyl 2,3-Bis[(trimethylsilyl)oxy]succinate; Diisopropyl (2R,3R)-2,3-Bis(trimethylsiloxy)succinate; (2R,3R)-2,3-Bis(trimethylsiloxy)succinic Acid Diisopropyl Ester; D-DIPT(TMS)2; Silyl-Protected D-DIPT; TMS-DIPT
EINECS	Contact for details

Quality Control

Our (-)-Diisopropyl O,O'-Bis(Trimethylsilyl) -D-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and NMR spectroscopy, to ensure it meets the high standards required for sensitive asymmetric synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.