Description

Ethanone, 1-[(1S,2S)-2-Phenylcyclopropyl]- (9Ci) is a chiral, enantiomerically pure cyclopropane derivative that serves as a valuable synthetic intermediate and building block in advanced organic synthesis. Its unique fused ring structure, combining a phenyl-substituted cyclopropane with a ketone functional group, makes it a critical precursor for constructing complex molecules with high stereochemical control. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its cyclopropane moiety can impart specific biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new chiral catalysts and the study of stereoselective reactions.
• Material Science Precursor: Potential intermediate for creating specialty polymers or liquid crystals with unique optical or electronic properties.
• Academic & R&D: A valuable tool in academic laboratories for methodological development in organic synthesis and stereochemistry studies.
• Flavor & Fragrance Industry: Can be utilized as an intermediate for synthesizing complex aroma chemicals with specific stereoisomeric profiles.

Basic Information

Product Name	Ethanone, 1-[(1S,2S)-2-Phenylcyclopropyl]- (9Ci)
CAS No.	196609-07-1
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	(1S,2S)-2-Phenylcyclopropyl methyl ketone; 1-[(1S,2S)-2-Phenylcyclopropyl]ethanone; (1S,2S)-1-Acetyl-2-phenylcyclopropane; (1S,2S)-2-Phenylcyclopropyl methyl ketone; trans-2-Phenylcyclopropyl methyl ketone; (1S,2S)-2-Phenylcyclopropan-1-yl methyl ketone; (1S,2S)-1-(2-Phenylcyclopropyl)ethanone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1S,2S)-2-Phenylcyclopropyl]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment. Our quality management system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,2S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.