Description

[6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl]Boronic Acid is a high-value organoboron building block, specifically a pyridine-substituted boronic acid derivative. This compound is essential for modern synthetic chemistry, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily utilized by pharmaceutical and agrochemical research and development teams for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoroethoxy-substituted pyridine motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoroethoxy group can impart favorable properties like weather resistance.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: The primary application is as a coupling partner with aryl or vinyl halides to construct biaryl and other conjugated systems critical in medicinal and materials chemistry.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.

Basic Information

Product Name	[6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl]Boronic Acid
CAS No.	196083-20-2
Molecular Formula	C7H7BF3NO3
Molecular Weight	220.94 g/mol
Synonyms	(6-(2,2,2-Trifluoroethoxy)pyridin-3-yl)boronic acid; 5-Borono-2-(2,2,2-trifluoroethoxy)pyridine; 2-(2,2,2-Trifluoroethoxy)-5-pyridineboronic acid; [6-(Trifluoroethoxy)-3-pyridyl]boronic acid; 3-Pyridineboronic acid, 6-(2,2,2-trifluoroethoxy)-; Boronic acid, B-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-; CAS 196083-20-2
EINECS	Contact for details

Quality Control

Our [6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.