Description

(2R,3S)-3-p-Tolyloxirane-2-Carboxamide CAS NO 195616-14-9 is a high-purity chiral epoxide derivative, serving as a critical synthetic intermediate and building block in advanced organic synthesis. Its defined stereochemistry makes it a valuable precursor for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where specific stereochemistry is required for biological activity.
• Asymmetric Synthesis: Employed as a building block in stereoselective reactions to introduce the oxirane (epoxide) functionality into target molecules.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring high enantiopurity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis research within university and corporate laboratories.
• Material Science: Potential use as a monomer or cross-linking agent in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	(2R,3S)-3-p-Tolyloxirane-2-Carboxamide
CAS No.	195616-14-9
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	(2R,3S)-3-(4-Methylphenyl)oxirane-2-carboxamide; (2R,3S)-3-(p-Tolyl)glycidamide; trans-3-(4-Methylphenyl)oxirane-2-carboxamide; (2R,3S)-3-(4-Methylphenyl)glycidamide; (2R,3S)-Epoxy-p-tolylpropionamide; (2R,3S)-3-(4-Methylphenyl)-2-oxiranecarboxamide; (2R,3S)-3-(p-Tolyl)oxiranecarboxamide; (2R,3S)-3-(4-Methylphenyl)-2,3-epoxypropanamide
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-p-Tolyloxirane-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment, ensuring full traceability and compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.