Description

3'-Chloro-4'-Fluoropropiophenone is a high-purity fluorinated and chlorinated aromatic ketone building block of significant synthetic utility. This compound matters as a versatile and critical intermediate in modern organic synthesis, enabling the efficient construction of complex molecules with precise halogen substitution patterns. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the halogenated aromatic core for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, carbonyl chemistry, and as a precursor for heterocyclic compounds in academic and industrial research.
• Chemical Reference Standard: Supplied as a certified standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	3'-Chloro-4'-Fluoropropiophenone
CAS No.	194943-82-3
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)propan-1-one; 3-Chloro-4-fluoropropiophenone; Propiophenone, 3'-chloro-4'-fluoro-; 4-Fluoro-3-chloropropiophenone; 3-Chloro-4-fluorophenyl ethyl ketone; 1-(3-Chloro-4-fluorophenyl)-1-propanone; 3'-Chloro-4'-fluoropropiophenon; 194943-82-3
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.