Description

2-Oxabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester,(1Alpha,5Beta,6Alpha)-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique strained bicyclic oxetane structure. This compound is of significant commercial value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Building Block: Utilized in advanced organic chemistry for constructing strained ring systems and introducing specific stereochemistry.
• Medicinal Chemistry Research: Serves as a valuable scaffold in drug discovery programs for exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for target molecules in pilot plant and commercial manufacturing.
• Asymmetric Catalysis Studies: Acts as a substrate or ligand precursor in the development of new asymmetric catalytic reactions.

Basic Information

Product Name	2-Oxabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester,(1Alpha,5Beta,6Alpha)-(9Ci)
CAS No.	194735-91-6
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	Ethyl (1α,5β,6α)-2-oxabicyclo[3.1.0]hexane-6-carboxylate; Ethyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate; (1R,5S,6S)-Ethyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate; 2-Oxabicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester; 194735-91-6; Bicyclic oxetane ester; Oxetane-fused cyclopropane carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Oxabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester,(1Alpha,5Beta,6Alpha)-(9Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.