Description

3-Hydroxycyclopentanecarbonitrile is a versatile chiral nitrile building block featuring both hydroxyl and nitrile functional groups on a cyclopentane ring. This compound matters as a critical intermediate for synthesizing complex pharmaceutical molecules and fine chemicals, enabling the introduction of stereochemistry and functional diversity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, cardiovascular, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry can influence biological activity.
• Fine Chemical Building Block: Serves as a precursor for the preparation of more complex molecules like amino alcohols, diamines, and carboxylic acids via transformation of its nitrile and hydroxyl groups.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Material Science Monomer: Investigated as a potential monomer for creating novel polymers with specific thermal or mechanical properties derived from its cyclic structure.

Basic Information

Product Name	3-Hydroxycyclopentanecarbonitrile
CAS No.	194534-83-3
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	3-Hydroxycyclopentanecarbonitrile; 3-Hydroxycyclopentane-1-carbonitrile; Cyclopentanecarbonitrile, 3-hydroxy-; 3-Cyano-1-cyclopentanol; 1-Cyano-3-cyclopentanol; (3-Hydroxycyclopentyl)cyanide; 3-Hydroxy-1-cyclopentanecarbonitrile; 3-Hydroxycyclopentyl nitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxycyclopentanecarbonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.