Description

Ru(Oac)2((R)-3,5-T-Bu-Meobiphep) is a highly efficient, chiral ruthenium(II) complex catalyst. It is specifically designed for asymmetric hydrogenation reactions, offering exceptional enantioselectivity and catalytic activity. This catalyst is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing chiral intermediates and active pharmaceutical ingredients (APIs). Its robust performance under optimized conditions makes it a valuable tool for scalable, stereoselective synthesis.

Application

• Asymmetric Hydrogenation of Functionalized Ketones: Enantioselective reduction of β-keto esters, α-keto acids, and related substrates to produce chiral alcohols.
• Pharmaceutical Intermediate Synthesis: Key catalyst for the production of chiral building blocks used in cardiovascular, central nervous system (CNS), and antiviral drug candidates.
• Fine Chemical and Agrochemical Manufacturing: Synthesis of enantiomerically pure compounds for advanced materials and high-value crop protection agents.
• Academic and Industrial R&D: A benchmark catalyst for method development and exploring new asymmetric transformation pathways in process chemistry.

Basic Information

Product Name	Ru(Oac)2((R)-3,5-T-Bu-Meobiphep)
CAS No.	194497-14-8
Molecular Formula	C52H66O4P2Ru
Molecular Weight	912.10 g/mol
Synonyms	Bis(acetato-κO)[(2R)-3,5-di-tert-butyl-4-methoxyphenyl][6-[[(2R)-3,5-di-tert-butyl-4-methoxyphenyl](phenyl)phosphino]-2-[2-(diphenylphosphino)phenyl]-4-phenyl-3,4-dihydro-2H-pyran-5-yl]phosphine]ruthenium; (R)-3,5-T-Bu-MeOBIPHEP Ru(II) diacetate complex; Ru((R)-3,5-tBu-MeOBIPHEP)(OAc)2; Chiral Ru-MeOBIPHEP catalyst; Asymmetric hydrogenation catalyst Ru-002; [Ru(OAc)2((R)-3,5-tBu-MeOBIPHEP)]
EINECS	Contact for details

Quality Control

Our Ru(Oac)2((R)-3,5-T-Bu-Meobiphep) is manufactured under strict quality-controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques, including NMR and HPLC, to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool environment. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.