Description

8Beta-Methoxyatractylenolide I is a bioactive natural product and a key chemical reference standard derived from the medicinal plant *Atractylodes macrocephala*. This compound is of significant interest for its role in quality control and pharmacological research, serving as a critical marker for the authentication and standardization of herbal extracts. It is primarily sought by analytical laboratories, pharmaceutical R&D departments, and manufacturers of botanical supplements who require high-purity reference materials to ensure product efficacy, consistency, and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of herbal medicines and extracts containing atractylenolides.
• Bioactivity and Pharmacological Research: Serves as a key compound in studies investigating anti-inflammatory, anti-cancer, and gastrointestinal regulatory activities.
• Herbal Medicine Quality Control: Acts as a marker compound for the standardization and authentication of *Atractylodes macrocephala* (Baizhu) raw materials and finished products.
• Analytical Method Development: Essential for developing and validating HPLC, UPLC, and LC-MS/MS methods in analytical laboratories.
• Nutraceutical and Dietary Supplement Manufacturing: Employed in the quality assurance process to guarantee the potency and consistency of botanical supplement formulations.
• Academic and Institutional Research: Used in universities and research institutes for phytochemical, metabolic, and biosynthetic pathway studies.

Basic Information

Product Name	8Beta-Methoxyatractylenolide I
CAS No.	193694-24-5
Molecular Formula	C17H22O5
Molecular Weight	306.36 g/mol
Synonyms	8β-Methoxyatractylenolide I; 8β-Methoxyatractylenolide; (3aR,4S,6aR,6bS,8aR,9S,12aS,14aR)-9-Methoxy-4,6a,6b,9,12a-pentamethyl-1,2,3,3a,4,5,6,6a,6b,7,8,8a,9,12,12a,13,14,14a-octadecahydropicene-3,10-dione; Atractylenolide I 8-methyl ether; 8-Methoxyatractylenolide I
EINECS	Contact for details

Quality Control

Our 8Beta-Methoxyatractylenolide I is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and structural confirmation via NMR and MS, to ensure it meets the high standards required for reference materials and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.