Description

1,3-Cyclopentanedicarboxyl Difluoride, 1,2,2-Trimethyl-, (1R-Cis)- (9Ci) is a high-purity, chiral fluorinated building block of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and reactive difluoride groups, which enable the efficient construction of complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where its fluorinated structure can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry: Acts as a versatile reagent for introducing the cyclopentane dicarboxylate motif with fluorine handles into target molecules.

Basic Information

Product Name	1,3-Cyclopentanedicarboxyl Difluoride, 1,2,2-Trimethyl-, (1R-Cis)- (9Ci)
CAS No.	193280-15-8
Molecular Formula	C10H12F2O2
Molecular Weight	202.20 g/mol
Synonyms	(1R,3S)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid difluoride; (1R-cis)-1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic Acid Difluoride; cis-1,2,2-Trimethylcyclopentane-1,3-dicarboxyl Difluoride; 1,3-Cyclopentanedicarboxylic acid, 1,2,2-trimethyl-, difluoride, (1R,3S)-rel-; Chiral Cyclopentane Difluoride Ester
EINECS	Contact for details

Quality Control

Our production of 1,3-Cyclopentanedicarboxyl Difluoride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.