Description

(S)-3-Boc-Amino-1-Diazo-4-Benzyloxy-2-Butanone is a high-value, chiral building block and diazo compound used in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing peptidomimetics and other bioactive scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral amino acid derivatives and constrained peptides for drug discovery programs.
• Peptidomimetic Synthesis: Used to introduce diazo and protected amino functionalities for creating protease inhibitors and other bioactive peptide analogs.
• Chemical Biology Probes: Serves as a building block for labeling reagents and activity-based probes targeting specific enzymes.
• Agrochemical Research: Employed in the development of novel, chiral active ingredients with specific modes of action.
• Academic & Industrial R&D: Utilized in methodological development for new C-H insertion and cyclopropanation reactions catalyzed by transition metals.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(S)-3-Boc-Amino-1-Diazo-4-Benzyloxy-2-Butanone
CAS No.	193148-60-6
Molecular Formula	C₁₆H₂₁N₃O₄
Molecular Weight	319.36 g/mol
Synonyms	(S)-1-Diazo-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]butan-2-one; (S)-3-[(tert-Butoxycarbonyl)amino]-1-diazo-4-(phenylmethoxy)-2-butanone; Boc-D-Aad(Bzl)-diazoketone; (S)-3-(Boc-amino)-1-diazo-4-benzyloxy-2-butanone; tert-Butyl N-[(2S)-1-diazo-4-(phenylmethoxy)-3-oxobutan-2-yl]carbamate; (S)-1-Diazo-3-(N-Boc-amino)-4-benzyloxy-2-butanone
EINECS	Contact for details

Quality Control

Our (S)-3-Boc-Amino-1-Diazo-4-Benzyloxy-2-Butanone is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.