Description

Potassium 4-Fluorophenyltrifluoroborate is an organoboron reagent widely used as a key building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity in cross-coupling reactions, enabling the efficient construction of complex fluorinated aromatic structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where precise fluorination is critical for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A stable and efficient boron reagent for forming carbon-carbon bonds with aryl halides, crucial for synthesizing biaryl compounds.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs) containing fluorophenyl motifs, which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor in creating novel herbicides, fungicides, and insecticides that benefit from the specific properties of fluorine atoms.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other advanced catalytic processes.
• Materials Science Research: A building block for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials where the fluorophenyl group modifies physical properties.
• Chemical Biology Probes: Useful for incorporating fluorinated tags into molecules for studying biological processes via techniques like 19F NMR.

Basic Information

Product Name	Potassium 4-Fluorophenyltrifluoroborate
CAS No.	192863-35-7
Molecular Formula	C6H4BF4K
Molecular Weight	205.99 g/mol
Synonyms	Potassium (4-Fluorophenyl)trifluoroborate; 4-Fluorophenyltrifluoroboronic Acid Potassium Salt; Potassium 4-Fluorobenzene-1-trifluoroborate; 4-Fluorophenyl-BF3K; (4-Fluorophenyl)trifluoroborate Potassium Salt; 4-Fluorophenyl Potassium Trifluoroborate; 4-Fluorophenyl-Boron, Trifluoro-, Potassium Salt; Potassium Trifluoro(4-fluorophenyl)borate
EINECS	Contact for details

Quality Control

Our Potassium 4-Fluorophenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high purity and consistent performance in sensitive applications like cross-coupling. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Potentiometric)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, methanol, DMF; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.