Description

Ethanone, 2,2-Difluoro-2-(Methylthio)-1-Phenyl- (9Ci) is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring both difluoro and methylthio substituents on a phenyl ethanone core, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the preparation of advanced pesticides and herbicides, where the difluoro group can improve biological activity and environmental persistence.
• Material Science Research: Acts as a monomer or precursor for specialty polymers and advanced materials with tailored surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis, leveraging the sulfur and fluorine atoms for metal coordination.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying the reactivity of α,α-difluoro thioethers.

Basic Information

Product Name	Ethanone, 2,2-Difluoro-2-(Methylthio)-1-Phenyl- (9Ci)
CAS No.	192862-16-1
Molecular Formula	C9H8F2OS
Molecular Weight	202.22 g/mol
Synonyms	2,2-Difluoro-2-(methylthio)-1-phenylethanone; 1-Phenyl-2,2-difluoro-2-(methylthio)ethanone; α,α-Difluoro-α-(methylthio)acetophenone; Difluoro(methylthio)phenylmethanone; (Difluoromethylsulfanyl)(phenyl)methanone; Phenyl 2,2-difluoro-2-(methylthio) ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Difluoro-2-(Methylthio)-1-Phenyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. This material is moisture-sensitive (hygroscopic); handle and store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.