Description

1-Fluoro-2-[(E)-2-Nitrovinyl]Benzene is a specialized fluorinated nitrovinylbenzene derivative, serving as a valuable synthetic intermediate in advanced organic chemistry. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those containing fluorinated aromatic systems and nitroalkene motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and nitrovinyl group can enhance biological activity and stability.
• Material Science Research: Employed as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a versatile scaffold for creating fluorescent tags, photoaffinity labels, and other molecular probes due to its reactive functional groups.
• Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) for creating complex biaryl structures.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	1-Fluoro-2-[(E)-2-Nitrovinyl]Benzene
CAS No.	192818-72-7
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	(E)-1-Fluoro-2-(2-nitrovinyl)benzene; 2-Fluoro-β-nitrostyrene; (E)-2-Fluoro-β-nitrostyrene; 1-Fluoro-2-[(E)-2-nitroethenyl]benzene; o-Fluoro-β-nitrostyrene; Benzene, 1-fluoro-2-[(E)-2-nitrovinyl]-; (E)-1-(2-Fluorophenyl)-2-nitroethene
EINECS	Contact for details

Quality Control

Our production of 1-Fluoro-2-[(E)-2-Nitrovinyl]Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.