Description

(S)-4-(2,4-Difluorophenyl)-2-(Hydroxymethyl)Pent-4-En-1-Ylisobutyrate CAS NO 192448-07-0 is a high-purity, chiral organic intermediate characterized by its specific stereochemistry and functional groups. This compound is of significant value in the pharmaceutical and fine chemical industries for the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new drug candidates, especially for antiviral, antifungal, or CNS-targeted therapies.
• Asymmetric Synthesis: Utilized in advanced organic synthesis to introduce the (S)-configured stereocenter and the difluorophenyl moiety into target molecules.
• Protease Inhibitor Precursor: Serves as a critical intermediate in the synthesis pathway for specific protease inhibitor类药物.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	(S)-4-(2,4-Difluorophenyl)-2-(Hydroxymethyl)Pent-4-En-1-Ylisobutyrate
CAS No.	192448-07-0
Molecular Formula	C16H20F2O3
Molecular Weight	298.33 g/mol
Synonyms	(S)-4-(2,4-Difluorophenyl)-2-(hydroxymethyl)-4-penten-1-yl isobutyrate; (S)-4-(2,4-Difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-yl 2-methylpropanoate; 192448-07-0; (S)-enantiomer of 4-(2,4-Difluorophenyl)-2-(Hydroxymethyl)Pent-4-En-1-Ylisobutyrate; SCHEMBL2388301; DTXSID60674469; Isobutyric acid, 4-(2,4-difluorophenyl)-2-(hydroxymethyl)-4-penten-1-yl ester, (S)-
EINECS	Contact for details

Quality Control

Our (S)-4-(2,4-Difluorophenyl)-2-(Hydroxymethyl)Pent-4-En-1-Ylisobutyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development with custom specifications aligned with GMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.