Description

2H-Azirine-2-Methanol, 3-Phenyl-, (2S)- (9Ci) is a chiral, non-racemic aziridine derivative, a high-value synthetic building block prized for its strained three-membered heterocyclic ring. This compound matters for its role as a versatile intermediate in asymmetric synthesis, enabling the stereoselective construction of complex nitrogen-containing molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in the synthesis of β-amino alcohols and other nitrogen heterocycles.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed reactions, enhancing enantioselectivity in industrial processes.
• Agrochemical Research: Serves as a building block for creating new pesticides and herbicides with specific stereochemical configurations.
• Academic & Process Chemistry: Employed in methodological studies for ring-opening and functionalization reactions to explore new synthetic pathways.
• Fine Chemical Synthesis: Utilized in the custom manufacturing of specialty chemicals requiring precise stereochemical control.

Basic Information

Product Name	2H-Azirine-2-Methanol, 3-Phenyl-, (2S)- (9Ci)
CAS No.	192370-02-8
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(2S)-3-Phenyl-2H-azirine-2-methanol; (S)-3-Phenyl-2H-azirine-2-methanol; (S)-2-(Hydroxymethyl)-3-phenylaziridine; 2H-Azirine-2-methanol, 3-phenyl-, (2S)-; (2S)-3-Phenylaziridine-2-methanol; Aziridine-2-methanol, 3-phenyl-, (2S)-; (S)-3-Phenylaziridine-2-carbinol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), tailored to meet specific research and process requirements. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.