Description

6-Fluoro-Chroman-4-Ylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key synthon for constructing complex molecules, particularly in medicinal chemistry research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with improved efficacy.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting exploratory organic synthesis and methodology development.
• Process Chemistry Development: Used to scale up and optimize synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	6-Fluoro-Chroman-4-Ylamine Hydrochloride
CAS No.	191609-45-7
Molecular Formula	C9H11ClFNO
Molecular Weight	203.64 g/mol
Synonyms	4-Amino-6-fluorochroman hydrochloride; 6-Fluorochroman-4-amine hydrochloride; 4-Amino-6-fluoro-3,4-dihydro-2H-1-benzopyran hydrochloride; 2H-1-Benzopyran-4-amine, 6-fluoro-3,4-dihydro-, hydrochloride (1:1); 6-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (4-Amino-6-fluoro-3,4-dihydro-2H-chromenyl) hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Fluoro-Chroman-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.