Description

Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester is a high-value, multifunctional bicyclic building block featuring a unique strained ring system. This compound is prized for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce constrained, three-dimensional frameworks into their target compounds. The CAS number for this product is 191399-80-1.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where its bicyclic structure can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties due to its strained ring geometry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor compounds requiring specific stereochemistry.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester
CAS No.	191399-80-1
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	Ethyl 2-Amino-2-cyano-4-methylbicyclo[3.1.0]hexane-6-carboxylate; 2-Amino-2-cyano-4-methylbicyclo[3.1.0]hexane-6-carboxylic Acid Ethyl Ester; Bicyclo[3.1.0]hexane-6-carboxylic acid, 2-amino-2-cyano-4-methyl-, ethyl ester; 191399-80-1; Ethyl 2-amino-2-cyano-4-methyl-6-bicyclo[3.1.0]hexanecarboxylate
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, handling and packaging should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.